Abstraction Health

Tongkat Ali

Adaptogen

Also known as: Eurycoma longifolia · Longjack · Malaysian ginseng · Pasak bumi

🟠Weak Evidence 64 expert mentions 4 studies
D·39/100·Limited
Research Depth5/25
Study Quality13/25
Expert Consensus17/25
Claim Support4/25
How we score the evidence →

A Southeast Asian herb studied for testosterone support, libido, and stress modulation. Standardized extracts (Physta) show modest but consistent testosterone-boosting effects in multiple trials.

Common forms:standardized extract (Physta)root powder

How expert claims hold up

64 of 64 claims assessed
1Supported10Partial53Insufficient

11 of 64 assessed claims supported or partially supported by published research

Expert Consensus

Research agrees
1/5
Experts mention
1
Recommend
1
Flag caution
Andrew Huberman
Andrew Huberman Recommends Caution
Research agrees64 claims200milligrams or 400milligramsstandardized extracthigh-potency standardized extract

Dose divergence: Experts recommend different amounts (200milligrams, 400milligrams). Check the Stack & Timing tab for study-backed dosing ranges.

Evidence Summary

PubMed / NCBI·May 2026
All 4 studies
4
Studies
1
RCTs
3
Reviews

Tongkat Ali (Eurycoma longifolia) is a Southeast Asian root extract with a long history of traditional use for male vitality, but the current clinical evidence supporting its marketed benefits is weak to insufficient. Out of 64 expert claims evaluated against this literature, 53 were rated as having insufficient evidence, 10 as partially supported, and only 1 as fully supported. The one rigorous human trial available — a 6-month double-blind RCT in aging males with androgen deficiency — combined Tongkat Ali with concurrent exercise training, which makes it impossible to attribute any observed effects to the supplement alone. Narrative and systematic reviews offer background on traditional use and chemistry, but do not substitute for robust clinical trial data. The most credible signal in the literature is a possible effect on testosterone levels, particularly free testosterone, in men with low androgen levels — but even this finding is only partially supported, and the evidence is not consistent across studies. Claims about erectile dysfunction improvement, muscle gain, stress reduction, and athletic performance enhancement are largely unsubstantiated in the current human research base. The existing systematic reviews on erectile dysfunction supplements flag Tongkat Ali as commonly included in products but lacking sufficient evidence to confirm efficacy. Significant limitations constrain what can be concluded. Study populations are small and narrow (primarily aging males with clinical androgen deficiency), making findings difficult to generalize to healthy adults. The confounding effect of exercise in the primary RCT is a major methodological issue. Standardization of Tongkat Ali extracts varies across products and studies, further complicating comparisons. Much of the underlying mechanistic research is from animal or in vitro studies, which do not reliably predict human outcomes. Until larger, well-controlled human trials are conducted in diverse populations, most benefit claims remain speculative.

Read full evidence summary →

Top studies

Medicina (Kaunas, Lithuania) · 2022 · Leisegang K et al.
Systematic Review🟢
Key finding

COI: The authors declare no conflict of interest.
PMID: 36013514DOI: 10.3390/medicina58081047
View on PubMed

An Analysis of Popular Online Erectile Dysfunction Supplements.

The journal of sexual medicine · 2019 · Balasubramanian A et al.
Systematic Review🟢
Key finding

An Analysis of Popular Online Erectile Dysfunction Supplements.

Funded by: NIDDK NIH HHS
PMID: 31036522DOI: 10.1016/j.jsxm.2019.03.269
View on PubMed

Expert Mentions

All 64 mentions
Andrew Huberman
Andrew Huberman
Stanford School of Medicine / Huberman Lab
Caution / warning

Quality control is a real issue in this category, so sourcing from reputable companies with third-party testing matters.

Extracted claim

Quality control is a real issue in the tongkat ali category; sourcing from reputable companies with third-party testing matters.

Insufficient evidence to assessHigh confidence

None of the four provided studies contain extractable key findings, populations, or limitations that directly address quality control, contamination, or third-party testing standards in the tongkat al…

Andrew Huberman
Andrew Huberman
Stanford School of Medicine / Huberman Lab
Caution / warning

Quality control is a real issue in this category, so sourcing from reputable companies with third-party testing matters.

Extracted claim

Quality control is a real issue in the tongkat ali category; sourcing from reputable companies with third-party testing matters.

Partially supportedHigh confidence

The systematic review (PMID: 36013514) and the ED supplements analysis (PMID: 31036522) provide contextual support for quality control concerns, as the latter specifically examined online ED supplemen…

Safety, interactions & who should avoid Tongkat Ali

generally_recognized_safe

The reviewed literature does not provide robust human safety data for Tongkat Ali, and no serious adverse events are prominently flagged in these studies, but the absence of reported harms should not be interpreted as confirmed safety given the limited trial scope and duration.

Tongkat Ali is generally considered well-tolerated at studied doses, but the review literature notes potential concerns around heavy metal contamination in some commercial products; long-term safety data beyond 6 months is limited. Some products marketed online have been found to contain undisclosed ingredients or adulterants.

Who should avoid it

Individuals with hormone-sensitive conditions (e.g., prostate cancer, breast cancer), those on immunosuppressants, pregnant or breastfeeding women, and children should avoid use. Those with liver or kidney conditions should consult a physician given limited long-term safety data.

Known interactions

  • ·May interact with immunosuppressant medications due to reported immunomodulatory activity
  • ·May theoretically potentiate hormonal therapies or testosterone replacement therapy — use caution

Pregnancy & breastfeeding

Our sources specifically flag pregnancy or breastfeeding considerations for Tongkat Ali — see the cautions above.

We don’t assign pregnancy-safety ratings. Many supplements lack adequate safety data in pregnancy and breastfeeding, and the absence of a warning here does not mean a supplement is safe to take. Don’t start, stop, or continue any supplement while pregnant or nursing without your OB-GYN or midwife.

Read: Supplements during pregnancy & breastfeeding →

This is educational information only. Consult a healthcare provider before starting any supplement.

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Key findings

  • ·Tongkat Ali is a root extract from Southeast Asia with centuries of traditional use for male vitality — this historical use is well-documented but does not confirm clinical efficacy.
  • ·The only human RCT identified was a 6-month placebo-controlled trial in aging males with androgen deficiency, but it combined Tongkat Ali with exercise training, making it impossible to isolate the supplement's effects.
  • ·Some evidence suggests a possible effect on free testosterone in men with low androgen levels, but this finding is only partially supported and inconsistent across studies.

Evidence gaps

  • ·No large, well-controlled RCTs isolating Tongkat Ali's effects (without co-interventions like exercise) in healthy or diverse adult populations exist in the current evidence base.
  • ·Long-term safety and efficacy data are lacking; most human studies are short-term and conducted in narrow populations (e.g., older males with androgen deficiency).
  • ·Extract standardization is inconsistent across commercial products and studies, making it difficult to determine what dose or formulation — if any — is effective.