Energy
Fatigue, low energy, physical performance
5 supplements with evidence · ordered by relevance
Creatine
Amino Acid DerivativeOne of the most researched supplements. Supports ATP regeneration, muscle strength, and cognitive function.
Magnesium
MineralAn essential mineral involved in over 300 enzymatic reactions. Widely studied for sleep, anxiety, and metabolic health.
Vitamin D
Fat-Soluble VitaminA fat-soluble vitamin critical for bone health, immune function, and mood regulation. Deficiency is widespread.
Taurine
Amino AcidTaurine is a sulfur-containing compound abundant in muscle, heart, retina, and brain. Unlike most amino acids, it is not incorporated into proteins but plays broad roles in osmoregulation, membrane stabilization, calcium homeostasis, bile acid conjugation, and antioxidant defense. Research interest has historically focused on cardiovascular health and exercise performance. A landmark 2023 paper in Science (Singh et al.) elevated interest in taurine's potential role in aging biology, finding that taurine declines with age and that supplementation extended lifespan in mice — an exciting finding that awaits human interventional replication.
Fish Oil / Omega-3
Essential Fatty AcidRich in EPA and DHA omega-3 fatty acids. Studied for cardiovascular, brain, and anti-inflammatory benefits.