Does Mark Hyman recommend Berberine?
Yes — Mark Hyman has directly recommended Berberine.
Published research rates it moderate evidence. Of Mark Hyman's 4 tracked claims, 2 are supported or partially supported by studies on PubMed.
Evidence last reviewed May 2026
Mark Hyman on Berberine — 4 claims
“certain supplements may be helpful with people with insulin resistance and I use them my practice like lipoic acid magnesium chromium berberine vitamin D Omega-3s all really helpful”
Berberine is a helpful supplement for people with insulin resistance, and Mark Hyman uses it in his practice.
“certain supplements may be helpful with people with insulin resistance and I use them my practice like lipoic acid magnesium chromium berberine vitamin D Omega-3s all really helpful”
Berberine is a helpful supplement for people with insulin resistance, and Mark Hyman uses it in his practice.
Multiple RCTs and meta-analyses in the provided literature support berberine's benefit for metabolic parameters related to insulin resistance. The RCT (PMID: 18442638) found berberine comparable to me…
“a lot of them are controlled by these phytochemicals whether it's green tea compounds berberine from different plants or all the weird things that can have profound effects”
Berberine, derived from plants, can activate longevity switches and has profound effects on health and healthy aging.
“a lot of them are controlled by these phytochemicals whether it's green tea compounds berberine from different plants or all the weird things that can have profound effects”
Berberine, derived from plants, can activate longevity switches and has profound effects on health and healthy aging.
The available evidence supports that berberine has meaningful metabolic effects — including improvements in blood glucose (PMID 18442638, showing effects comparable to metformin), lipid profiles (PMID…
Other supplements Mark Hyman discusses
Claims are extracted from publicly available podcasts and videos, attributed to their source, and compared against PubMed research. This is educational information only — consult a healthcare provider before starting any supplement.
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