Spermidine
PolyamineA naturally occurring polyamine found in wheat germ, soybeans, and aged cheese. Studied for autophagy induction, longevity, cardiovascular health, and cognitive function.
Evidence comparisons not yet run for these claims.
Expert Consensus
Expert Mentions
All 12 mentions
“The one that stands out for me is the one by Schwartz et al 2018. They were giving people 1.2 g per day over 3 months and there was significant enhancement of memory.”
A study by Schwartz et al. 2018 gave people 1.2 g of spermidine per day over 3 months and found significant enhancement of memory.
“There've been a number of human studies on spermidine uh particularly revolving around enhancing memory and dealing with memory loss in older Americans. That's true. We don't know a lot about aging itself but cognition has greatly improved in a number of studies.”
Human studies on spermidine have shown enhancement of memory and improvement in memory loss in older individuals.
Safety, interactions & who should avoid Spermidine
We don’t have documented safety concerns or interactions for Spermidine in our current sources. That isn’t a guarantee of safety — talk to a healthcare provider, especially if you’re pregnant, nursing, or taking medication.
Pregnancy & breastfeeding
We don’t assign pregnancy-safety ratings. Many supplements lack adequate safety data in pregnancy and breastfeeding, and the absence of a warning here does not mean a supplement is safe to take. Don’t start, stop, or continue any supplement while pregnant or nursing without your OB-GYN or midwife.
Read: Supplements during pregnancy & breastfeeding →This is educational information only. Consult a healthcare provider before starting any supplement.
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